1. Volberding PA, Lagakos SW, Koch MA, et
al. Zidovudine in asymptomatic human immunodeficiency virus
infection -- a controlled trial in persons with fewer than 500
CD4-positive cells per cubic millimeter. N Engl J Med
1990;322:941-9.
Return to:
Text
2. Volberding PA, Lagakos SW, Grimes JM,
et al. The duration of zidovudine benefit in persons with
asymptomatic HIV infection: prolonged evaluation of protocol 019
of the AIDS Clinical Trials Group. JAMA 1994;272:437-42.
Return to:
Text
3. Concorde Coordinating Committee.
Concorde: MRC/ANRS randomised double-blind controlled trial of
immediate and deferred zidovudine in symptom-free HIV infection.
Lancet 1994;343:871-81.
Return to:
Text
4. Volberding PA, Lagakos SW, Grimes JM,
et al. A comparison of immediate with deferred zidovudine therapy
for asymptomatic HIV-infected adults with CD4 cell counts of 500
or more per cubic millimeter. N Engl J Med 1995;333:401-7.
Return to:
Text
5. Kinloch-de Loes S, Hirschel BJ, Hoen B,
et al. A controlled trial of zidovudine in primary human
immunodeficiency virus infection. N Engl J Med 1995;333:408-13.
Return to:
Text
6. Zhu T, Mo H, Wang N, et al. Genotypic
and phenotypic characterization of HIV-1 in patients with primary
infection. Science 1993;261:1179-81.
Return to:
Text
7. Zhang LQ, MacKenzie P, Cleland A,
Holmes EC, Leigh Brown AJ, Simmonds P. Selection for specific
sequences in the external envelope protein of human
immunodeficiency virus type 1 upon primary infection. J Virol
1993;67:3345-56.
Return to:
Text
8. Wolinsky SM, Wike CM, Korber BT, et al.
Selective transmission of human immunodeficiency virus type-1
variants from mother to infants. Science 1992;255:1134-7.
Return to:
Text
9. Wei X, Ghosh SK, Taylor ME, et al.
Viral dynamics in human immunodeficiency virus type 1 infection.
Nature 1995;373:117-22.
Return to:
Text
10. Ho DD, Neumann AU, Perelson AS, Chen
W, Leonard JM, Markowitz M. Rapid turnover of plasma virions and
CD4 lymphocytes in HIV-1 infection. Nature 1995;373:123-6.
Return to:
Text
11. Coffin JM. HIV population dynamics in
vivo: implications for genetic variation, pathogenesis, and
therapy. Science 1995;267:483-9.
Return to:
Text
12. Preston BD, Poiesz BJ, Loeb LA.
Fidelity of HIV-1 reverse transcriptase. Science
1988;242:1168-71.
Return to:
Text
13. Piatak M Jr, Saag MS, Yang LC, et al.
High levels of HIV-1 in plasma during all stages of infection
determined by competitive PCR. Science 1993;259:1749-54.
Return to:
Text
14. Cao Y, Ho DD, Todd J, et al. Clinical
evaluation of branched DNA signal amplification for quantifying
HIV type 1 in human plasma. AIDS Res Hum Retroviruses
1995;11:353-61.
Return to:
Text
15. Daar ES, Moudgil T, Meyer RD, Ho DD.
Transient high levels of viremia in patients with primary human
immunodeficiency virus type 1 infection. N Engl J Med
1991;324:961-4.
Return to:
Text
16. Clark SJ, Saag MS, Decker WD, et al.
High titers of cytopathic virus in plasma of patients with
symptomatic primary HIV-1 infection. N Engl J Med
1991;324:954-60.
Return to:
Text
17. Ho DD, Moudgil T, Alam M.
Quantitation of human immunodeficiency virus type 1 in the blood
of infected persons. N Engl J Med 1989;321:1621-5.
Return to:
Text
18. Mellors JW, Kingsley LA, Rinaldo CR
Jr, et al. Quantitation of HIV-1 RNA in plasma predicts outcome
after seroconversion. Ann Intern Med 1995;122:573-9.
Return to:
Text
19. Eron J, Benoit S, Jemsek J, Quinn J,
Fallon MA, Rubin M. A randomized double-blind multicenter
comparative trial of lamivudine (3TC) monotherapy vs. zidovudine
(ZDV) monotherapy vs. 3TC + ZDV combination in naive patients
with CD4 cell counts of 200-500/mm3. In: Program and
abstracts of the Second National Conference on Human Retroviruses
and Related Infections, Washington, D.C., February 1, 1995.
Washington, D.C.: American Society for Microbiology, 1995:173.
abstract.
Return to:
Text
20. Kempf DJ, Marsh KC, Denissen JF, et
al. ABT-538 is a potent inhibitor of human immunodeficiency virus
protease and has high oral bioavailability in humans. Proc Natl
Acad Sci U S A 1995;92:2484-8.
Return to:
Text
21. Vacca JP, Dorsey BD, Schleif WA, et
al. L-735,524: an orally bioavailable human immunodeficiency
virus type 1 protease inhibitor. Proc Natl Acad Sci U S A
1994;91:4096-100.
Return to:
Text