HIV and AIDS

A). Four viruses are shown budding from the surface of a cultured human lymphoma cell ( x 63,000). Like other enveloped viruses, HIV is unable to make lipids. The virus uses the lipid component of the membrane of the host cell as part of its envelope. During assembly at the cell surface, the viral envelope incorporates viral glycoprotein into the cell membrane. The membrane proteins of the cell are left behind when the virus buds off. Mature viruses are shown in( x 50,000).

B). The central dark spot in each virion is a cone-shaped core containing the RNA genome, reverse transcriptase, and core proteins. More on the budding of HIV

1. HIV Therapeutics

2. A Treatment Strategy

3. Evolutionary biology of HIV; Comment on HIV "quasi-species"

4. Development of a vaccine against HIV

5. HIV escape from immune control

6. Viral load and latently infected cells: Comment on the pathogenicity of HIV

7. HIV-1 infection of lymphocytes, macrophages, and dendritic cells

8. Transmission of HIV and HCV

9. Tat activation of T-cells and productive infection

10. HIV non-structural genes and T-cell depletion in mice

11. Chemokine co-receptors and HIV-1 infection

12. Th1/Th2 cytokines and HIV specific CTL

13. Viral production from macrophages during opportunistic infections

14. Complement and HIV infection

15. Marijuana and AIDS

16. Wasting Symdrome

17. AID$ IS BIG BUSINESS/BIG $$$

18. The cost of treating AIDS patients

19. Condom use and HIV infection in Thailand

20. Antibody inhibition/enhancement of HIV-1 infection

21. Herpesvirus and AIDS-Associated Kaposi's Sarcoma

22. No evidence of niche selection in HIV-1

23. Transendothelial migration of HIV infected lymphocytes