VIRAL LIGANDS, RECEPTORS, AND TARGET CELL(S)
| Virus | Viral ligand | Target cell | Cell
receptor(s) |
|---|
| Epstein-Barr virus | glycoprotein, gp, 350/220 | B-cells, epithelial
cells | CD21 (Complement receptor 2, CR2) |
| Coronavirus | gp180 | respiratory and intestional
epithelium | aminopeptidase N |
| HIV | gp120 | CD4+ T-cells, macrophages | CD4
molecule, chemokine receptors |
| Herpes simplex virus | gp gC | epithelial cells (productive
infection); neurons (latent infection) | heparan sulfate on proteoglycans
|
| Influenza virus | hemagglutinin | respiratory
epithelium | salic acid on glycoprotein |
| Poliovirus | viral protein 1 (VP1) | intestional
epithelium | molecule of the immunoglobin superfamily |
| Parainfluenza virus | H-N glycoproteins | respiratory
epithelium | gangliosides GD1a, GQ16 |
| Rhinovirus | VP1, VP3 | nasal
epithelium | ICAM-1 |
| Rotovirus | VP4, VP 7 | intestional
epithelium | acetylated salic acid on gylcoprotein |
| Vaccina virus | vaccina virus growth factor (VGF) | various
cells | epidermal growth factor receptor
|